| |
|
|
| |
EVENT DETAILS |
Roel Veraak, PhD
Professor
Associate Director of Computational Biology
The Jackson Laboratory of Genomic Medicine
"Molecular delineation of disease progression in glioma"
Individual cancers are comprised of populations of genetically distinct, separated subclones that compete for resources during the disease course, leading to dynamic evolutionary processes. High throughput technologies provide a snapshot of the disease process in space & time. To better understand therapy resistance & apply precision therapeutics, a more refined understanding of glioma evolution is required that can only be provided by multi-dimensional tumor sampling. The Verhaak Lab has characterized glioma across multiple dimensions in order to delineate evolutionary patterns, to inform optimal sampling for clinical decision making, & to demonstrate that extrachromosomal DNA elements play a critical role in gliomagenesis.
Roel Verhaak, PhD, is a Professor & the Associate Director of Computational Biology at the Jackson Laboratory of Genomic Medicine in Farmington, CT. The Verhaak Lab focuses on mechanisms of resistance to therapy in glioma, which the group mainly interrogates through sequencing & computational biology approaches on patient samples & experimental models. The lab have previously published on the genomic characterization of primary adult glioma, work that has led to revised classification of the disease followed by neuropathologists & the glioma community worldwide.
To learn more about Dr. Verhaak, visit his lab page & Google Scholar, Roel Verhaak, PhD.
|
|
|
|
|
|
