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Guardant Health develops breakthrough diagnostic technologies to improve cancer management. With Guardant360, we offer real-time, biopsy-free tumor sequencing that tracks tumor genomics in real-time & identifies associated treatment options. The assay is used by more than 6,000 oncologists & we partner with more than 50 biopharma companies.

Guardant Health raised over $550M from Sequoia Capital, Khosla Ventures, Lightspeed Ventures, OrbiMed & Softbank, before having a successful IPO on NASDAQ in 2018. Guardant is led by a seasoned management team of thought leaders & successful serial entrepreneurs in next generation sequencing & rare cell diagnostics. They are advised by an oncologist-led medical steering committee from leading cancer centers.

Job Description

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Manager to lead the Technology Development Data Generation team, supporting development & testing of sample preparation technologies for rare variant & epigenetic studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies & work with leaders in many different fields to create the most impactful & meaningful technologies for cancer management.

As a Manager to lead the Technology Development Data Generation team, you will work with members within the team as well as interface with multiple other teams including process engineering, bioinformatics, quality & operations. You will lead a team of 1-3 laboratory staff in the use of existing assays and/or assay prototypes to generate data in support of new technologies, as well as working alongside the team hands-on in the lab. You will plan & prioritize data generation runs in coordination with technology development, process engineering & bioinformatics teams. You have a detail-oriented & flexible attitude & can succeed in navigating the use of early assay versions to reliably output development data.

Experience in development & application of automated NGS assays is a must.Preference is given to candidates with experience in the development/operations interface.

Essential Duties & Responsibilities:

  • Run sequencing sample preparation assays in medium to high throughput environment using automated or semi-automated workflows
  • Professional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)
  • Manage, organize, & prioritize the data generation activities of team members
  • Detail-oriented capable planner with a flexible mindset a must
  • Create & maintain processes to track multiple sample preparation releases (SOPs, automation scripts & reagents) within the technology development team
  • Collaborate cross-functionally to juggle priorities & ensure assay performance
  • Identify areas for improvement in assay work stream & propose solutions
  • Ensure all work is performed & documented in compliance with applicable regulatory & quality practices (Design Control)
  • Present data, proposals, & progress in various forums
  • Foundation in molecular biology techniques including sample preparation for NGS
  • Sense of humor required
  • Consummate team player: demonstrated ability to thrive in an environment where numerous contributions are required to accomplish complex goals
  • Enjoy working independently & collaboratively in a fast-paced environment & able to adapt to change

PhD in Molecular Biology, Genetics, Biochemistry or related field & 5+ years of relevant work experience, or MS in Molecular Biology, Genetics, Biochemistry or related field with10+ years of relevant work experience.

Additional Information

All your information will be kept confidential according to EEO guidelines.

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