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Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets & advanced analytics. Its Guardant Health Oncology Platform is designed to leverage its capabilities in technology, clinical development, regulatory & reimbursement to drive commercial adoption, improve patient clinical outcomes & lower healthcare costs. In pursuit of its goal to manage cancer across all stages of the disease, Guardant Health has launched multiple liquid biopsy-based tests, Guardant360 & GuardantOMNI, for advanced stage cancer patients, which fuel its LUNAR development programs for recurrence & early detection. Since its launch in 2014, Guardant360 has been used by more than 6,000 oncologists, over 50 biopharmaceutical companies & all 27 of the National Comprehensive Cancer Network centers.

Job Description

The Bioinformatics Analyst II will help support the bioinformatics & data analysis necessary to generate & maintain Clinical Genomics activities. As a part of the Bioinformatics & Clinical Genomics teams, you will have the opportunity to innovate & implement your ideas to constantly improve our product & analytics so that they are best suited for the changing landscape of clinical needs.

Essential Duties & Responsibilities:

  • Provide analytic support to Medical Affairs & Clinical Operations

  • Work with a variety of Clinical Genomics customers & tailor personalized analyses for each stake holder.

  • Work with members of the bioinformatics group, medical affairs, & research scientists to conduct relevant analysis regarding clinical data & the performance of bioinformatics products.

  • Explore genomic data from clinical & research samples & external annotation sources to enhance quality of clinical reporting.

  • Develop scripts for research & development activities.

  • Work together with our collaborators in industry, hospitals & academia on high-impact translational research using Guardant Health tests & publish on findings.


  • B.S. or M.S. in bioinformatics or biological sciences

  • 3-5 years relevant experience.

  • Knowledge of cancer genomics & tumor biology

  • Experience with Human genetics & Cancer genetics databases e.g. (ExAC, ClinVar)

  • Experience using scripting languages (R, Python or Shell)

  • Knowledge of standard bioinformatics tool e.g. SAMtools, Picard, etc.

  • Working knowledge of statistical methods

  • Great communication & presentation skills, ability to present clearly & effectively to stakeholders across organizations

  • Ability to work well in a fast-paced startup environment

  • Desire & ability to dig deeply through various data types to seek out answers

  • Strong team player: ability to work together with the team as well as cross-functionally & even across institutions.

Additional Information

Employee may be required to lift routine office supplies & use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, & biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status & will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health & how it is used, please review ourPrivacy Notice for Job Applicants

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