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Helix // DNA-powered products
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You + Helix

Helix is a place where innovators & doers gather in order to drive significant progress in population genomics. We have come together to work at the intersection of clinical care, research, & genomics.  

If youre excited by the idea of making a meaningful impact & joining a team where we pride ourselves on driving innovation through fostering an environment with an emphasis on empowering one another to grow, Helix might be the place for you!

Helix + The World

Our end-to-end population genomics platform enables health systems, life sciences companies, & payers to advance genomic research & accelerate the integration of genomic data into routine clinical care. We support all aspects of population genomics from recruitment to translational research & help our partners use genomics to improve health outcomes, increase patient engagement, & lower costs. Leading health systems, including Renown Health, AdventHealth, & Mayo Clinic, use our population genomics platform to power some of the worlds largest & fastest-growing population genomics initiatives.

For the COVID-19 public health crisis, Helix has built one of the nations largest COVID diagnostic labs & has been on the leading edge of national viral surveillance efforts tracking B.1.1.7 & other viral strains.    

What is special about this role:

Lead large-scale architecture initiatives & build Platform services that broadly impact Helix Engineering & our partners.

As a Principal Software Engineer, you will:

  • Architect robust distributed systems designs that are highly secure & performant.

  • Code systems & components that support wide-ranging product lines at Helix, from genomics to viral surveillance, lab systems to diagnostics.

  • Innovate on healthcare data access patterns & interoperability in order to improve health equity.

  • Collaborate with product managers, bioinformaticians, & scientists to build platform services.

  • Establish strong engineering practices that are adopted across the organization.

  • Mentor other engineers to reinforce a culture of learning & teaching.


  • 10+ years development experience Go, Python, Java, Javascript, or a similar language

  • Expertise developing software on public cloud platforms AWS, Azure, or GCP

  • Affinity for an engineering culture that emphasizes agile, DevOps, & continuous delivery

  • A proven track record of successful, large-scale projects


  • BS+ in Computer Science; coursework in genetics or bioinformatics

  • Familiarity with regulated software systems & entities

  • Familiarity with full-stack development

What Helix Has to Offer you

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, & thoughtful people, we also provide great benefits:

  • Competitive compensation, including meaningful equity
  • Health insurance, including medical, dental, & vision
  • 12 weeks of Maternity or Paternity leave
  • 4 weeks of paid Pregnancy Disability
  • 401(k) with employer matching
  • On-premise nursing room
  • Commuter benefits
  • Catered meals
  • Flexible PTO

Helix is proud to be an equal opportunity employer, & committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth & breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, & local laws.

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